Studies on Phytochemical Screening of Leaf Fraction of Lantana camara Linn
نویسنده
چکیده
Background: The study was conducted to determine the antimicrobial activity of varying concentrations of Lantana camara Linn. leaf extracts against Staphylococcus aureus, Bacillus subtilis and Escherichia coli. Methods: Broth microdilution method was used to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) was evaluated through streaking of bacterial suspension onto Mueller-Hinton agar. Phytochemical tests were done to identify bioactive compounds present in the extracts. Results and Discussion: The results showed that among extracts used, L.camara leaf ethanolic fraction (EF) demonstrate best antibacterial activity. The MIC of ethanolic fraction ranges from at 1,250μg/mL – 5,000μg/mL. Bacillus subtilis is the most sensitive organism inhibited at 312.5 μg/mL. The MIC-MBC ratio revealed that the extracts possess bactericidal activity against test bacteria. Phytochemical evaluation indicates the presence of saponins, tannins and terpenoids in EF. Conclusion: L.camara leaf ethanolic fraction showed antibacterial activity and contain phytochemicals responsible for the broad antibacterial spectrum of the plant which may lead to new drug development
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Lantana Camara Linn. Chemical Constituents and Medicinal Properties: A Review
India has a rich tradition of plant based knowledge in health care. Among the large number of herbal drugs existing in India, very few have been studied systematically so far. Lantana camara is an evergreen plant found throughout India. Traditionally it has been used in treating various ailments and they were supported by scientific data’s. Various literatures have reported the phytoconstituent...
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